![](../../files/images/goods/623-05-2.png)
4-Hydroxybenzyl alcohol
CAS No. 623-05-2
4-Hydroxybenzyl alcohol ( —— )
产品货号. M18916 CAS No. 623-05-2
4-Hydroxybenzylool 在脑缺血性损伤中表现出有益作用,通过 PI3K/Akt 途径上调 Nrf2、Prdx6 和 PDI 表达而具有神经保护作用。
纯度: >98% (HPLC)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
![](/themes/theme/en/images/pdf.png)
规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥235 | 有现货 |
![]() ![]() |
1G | 获取报价 | 有现货 |
![]() ![]() |
生物学信息
-
产品名称4-Hydroxybenzyl alcohol
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述4-Hydroxybenzylool 在脑缺血性损伤中表现出有益作用,通过 PI3K/Akt 途径上调 Nrf2、Prdx6 和 PDI 表达而具有神经保护作用。
-
产品描述4-Hydroxybenzyl alcohol exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway. 4-Hydroxybenzyl alcohol inhibit the development of new blood vessels by targeting multiple mechanisms of the angiogenic process, may as a promising candidate for the establishment of anti-angiogenic treatment strategies in cancer therapy.
-
体外实验4-Hydroxybenzyl alcohol inhibits proliferation of eEND2 cells and suppresses the migration of eEND2 cells, accompanied by inhibition of actin filament reorganization.4-Hydroxybenzyl alcohol induces apoptotic death of tumor cells.
-
体内实验4-Hydroxybenzyl alcohol possesses antiangiogenic, anti-inflammatory and anti-nociceptive activity possibly via its down-regulating activity on NO production. 4-Hydroxybenzyl alcohol (200 mg/kg) efficiently inhibits growth and angiogenesis of developing tumors.4-Hydroxybenzyl alcohol ameliorates ischemic injury induced by transient focal cerebral ischemia in rats, and this neuroprotective effect may be partly related to attenuate apoptosis pathway.
-
同义词——
-
通路Others
-
靶点Other Targets
-
受体Others
-
研究领域Others-Field
-
适应症——
化学信息
-
CAS Number623-05-2
-
分子量124.14
-
分子式C7H8O2
-
纯度>98% (HPLC)
-
溶解度DMSO : 100 mg/mL; 805.54 mM
-
SMILESC1=CC(=CC=C1CO)O
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Laschke MW,et al.4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth. 2013 Jul 19;93(1):44-50.
产品手册
![](/themes/theme/en/images/ct.png)
![](/themes/theme/en/images/new12.jpg)
![](/themes/theme/en/images/gift.jpg)
![](/themes/theme/en/images/ct2.png)
关联产品
-
Picfeltarraenin IB
Picfeltarraenin IB 和 Picfeltarraenin IA 在体外人肿瘤细胞系组中不显示细胞毒性活性。
-
Rosarin
Rosarin 具有抗炎和神经保护作用。 Rosarin 抑制小鼠肾脏和大脑前额皮质中促炎因子 iNOS、IL-1 β 和 TNF-α 的表达。
-
JAG-1, scrambled
This peptide is a scrambled sequence of JAG-1(188-204).